Freezing of gait in early Parkinson's disease: Nigral iron content estimated from magnetic resonance imaging.
Identifieur interne : 000350 ( Main/Exploration ); précédent : 000349; suivant : 000351Freezing of gait in early Parkinson's disease: Nigral iron content estimated from magnetic resonance imaging.
Auteurs : Marguerite Wieler [Canada] ; Myrlene Gee [Canada] ; Richard Camicioli [Canada] ; W R Wayne Martin [Canada]Source :
- Journal of the neurological sciences [ 1878-5883 ] ; 2016.
English descriptors
- KwdEn :
- Aged, Female, Gait (physiology), Humans, Image Processing, Computer-Assisted, Iron (metabolism), Magnetic Resonance Imaging, Male, Middle Aged, Parkinson Disease (metabolism), Parkinson Disease (pathology), Parkinson Disease (physiopathology), Substantia Nigra (metabolism), Substantia Nigra (pathology).
- MESH :
- chemical , metabolism : Iron.
- metabolism : Parkinson Disease, Substantia Nigra.
- pathology : Parkinson Disease, Substantia Nigra.
- physiology : Gait.
- physiopathology : Parkinson Disease.
- Aged, Female, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Middle Aged.
Abstract
Freezing of gait is a major source of disability associated with the progression of Parkinson's disease (PD). Our objective was to determine whether evolving changes in nigral iron content in association with declining motor function in early PD differentiates subjects who develop freezing from those who do not.
DOI: 10.1016/j.jns.2015.12.008
PubMed: 26810522
Affiliations:
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Le document en format XML
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Electronic address: wmartin@ualberta.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Neurology, University of Alberta, Edmonton, Alberta</wicri:regionArea><wicri:noRegion>Alberta</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of the neurological sciences</title><idno type="eISSN">1878-5883</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Female</term><term>Gait (physiology)</term><term>Humans</term><term>Image Processing, Computer-Assisted</term><term>Iron (metabolism)</term><term>Magnetic Resonance Imaging</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (metabolism)</term><term>Parkinson Disease (pathology)</term><term>Parkinson Disease (physiopathology)</term><term>Substantia Nigra (metabolism)</term><term>Substantia Nigra (pathology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Iron</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Parkinson Disease</term><term>Substantia Nigra</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Parkinson Disease</term><term>Substantia Nigra</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Gait</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Female</term><term>Humans</term><term>Image Processing, Computer-Assisted</term><term>Magnetic Resonance Imaging</term><term>Male</term><term>Middle Aged</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Freezing of gait is a major source of disability associated with the progression of Parkinson's disease (PD). Our objective was to determine whether evolving changes in nigral iron content in association with declining motor function in early PD differentiates subjects who develop freezing from those who do not.</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><country name="Canada"><noRegion><name sortKey="Wieler, Marguerite" sort="Wieler, Marguerite" uniqKey="Wieler M" first="Marguerite" last="Wieler">Marguerite Wieler</name></noRegion><name sortKey="Camicioli, Richard" sort="Camicioli, Richard" uniqKey="Camicioli R" first="Richard" last="Camicioli">Richard Camicioli</name><name sortKey="Gee, Myrlene" sort="Gee, Myrlene" uniqKey="Gee M" first="Myrlene" last="Gee">Myrlene Gee</name><name sortKey="Martin, W R Wayne" sort="Martin, W R Wayne" uniqKey="Martin W" first="W R Wayne" last="Martin">W R Wayne Martin</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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